Regenerative skincare has become one of the most exciting areas in aesthetic medicine, and two treatments often lead the conversation. Platelet Rich Plasma, known as PRP, and Platelet Rich Fibrin, known as PRF. Both therapies use your body’s own platelets and growth factors to support collagen production and rejuvenate the skin in a natural and long lasting way. For clients who want subtle improvement without synthetic fillers or dramatic procedures, PRP and PRF are powerful options.
At The Lounge at Healdsburg, these treatments are popular among clients looking for refreshed, glowing skin with very natural results. While PRP and PRF share similarities, they are not identical. Each has its own strengths, its own applications, and its own ideal uses. Understanding the difference can help you choose the right treatment for your goals, your skin, and your stage of aging.
Below, we will break down how each treatment works, what makes them different, and how to know which one might be the best fit for your skin.
What PRP Is and How It Works
PRP, Platelet Rich Plasma, has been used in medical settings for decades. It is known for its healing properties and its ability to help repair tissue. In aesthetics, PRP is widely used to improve tone, texture, and elasticity. The treatment begins with a small amount of your blood being drawn and placed in a centrifuge. This separates the plasma, which is rich in platelets, from the red and white blood cells.
Platelets are packed with growth factors. These growth factors signal your skin to regenerate, repair, and rebuild. When PRP is injected or applied during treatments such as microneedling, it encourages collagen production and improves overall skin health.
What PRP can help improve
• Early fine lines
• Rough texture
• Mild pigmentation
• Dull or tired looking skin
• Minor acne scarring
• Skin that needs a general boost in vitality
PRP is a gentle regenerative treatment that blends well with a wide range of skincare goals. Results appear gradually and continue improving over several weeks.
What PRF Is and How It Works
PRF, Platelet Rich Fibrin, is considered the next generation of platelet therapy. Like PRP, it starts with a simple blood draw. However, the preparation process is different. PRF is spun at a slower speed, which creates a higher concentration of platelets, white blood cells, stem cells, and fibrin. The result is a thicker, more natural matrix that releases growth factors slowly over time.
This slower release leads to longer lasting rejuvenation. Because PRF contains a fibrin scaffold, it continues to deliver regenerative benefits in the days and weeks after treatment.
What PRF can help improve
• Under eye hollows and dark circles
• Moderate fine lines and deeper texture concerns
• Loss of elasticity
• Thinning or fragile skin
• More advanced signs of aging
• Areas that benefit from gradual volume support
PRF can be injected or applied topically, depending on the treatment plan. It is especially popular for delicate areas where traditional fillers may not be the best option.
Key Differences Between PRP and PRF
Although PRP and PRF share the same goal, they are prepared differently and work in slightly different ways. These distinctions influence how long results last, how treatments are used, and what improvements clients can expect.
Concentration of platelets
PRF contains a higher concentration of platelets and white blood cells than PRP. This means more growth factors and stronger regenerative potential.
Release of growth factors
PRP releases growth factors quickly after treatment. PRF releases them slowly over a longer period, creating extended improvement.
Presence of fibrin
PRF contains fibrin, which forms a gentle matrix that supports tissue regeneration. This fibrin structure helps hold shape and adds subtle volume in some areas.
Strength of rejuvenation
PRP is excellent for overall tone and mild texture improvement. PRF is better for deeper rejuvenation, under eye concerns, and more advanced aging needs.
Longevity
Because of its slow release, PRF often lasts longer than PRP. Results may continue improving for several months.
Both treatments are natural, safe, and effective. The right choice depends on your goals and what you hope to improve.
How PRF EZ Gel Fits Into Regenerative Aesthetics
In addition to traditional PRF, The Lounge at Healdsburg offers PRF EZ Gel. This is an advanced treatment that combines PRF with your body’s albumin to create a smooth, gel-like injectable product.
PRF EZ Gel provides a level of subtle volume and structure while still being completely natural. It slowly releases growth factors while simultaneously offering gentle lift or fullness in areas that need it.
Why clients love PRF EZ Gel
• 100 percent natural ingredients
• Adds soft volume without synthetic fillers
• Improves texture and elasticity
• Excellent for under eyes, nasolabial folds, or fine creases
• Long lasting, subtle results
This option is ideal for clients who want volume support but prefer a natural approach.
Which Treatment Is Best for You
Your ideal treatment depends on your skin concerns, your stage of aging, and the level of improvement you want. Here is a simple guide to help you understand which treatment may fit your goals.
Choose PRP if
• You want a gentle refresh
• Your concerns are mild
• You want better brightness and smoother texture
• You are in your 20s or 30s and focused on prevention
• You want to pair it with microneedling
PRP is like giving your skin a natural boost. It enhances overall vitality without structural changes.
Choose PRF if
• You want stronger, longer lasting rejuvenation
• You have deeper texture concerns or moderate fine lines
• You want to improve under eye hollows or dark circles
• You are in your 30s, 40s, or 50s with more advanced signs of aging
• You want natural but noticeable improvement over time
PRF supports collagen and elasticity with more strength than PRP.
Choose PRF EZ Gel if
• You want subtle volume that still looks incredibly natural
• You want an alternative to synthetic fillers
• You want improvement under the eyes that looks soft and balanced
• You prefer treatments made from your own cells
PRF EZ Gel is ideal for those who want both rejuvenation and light structural support.
What to Expect During Treatment
Both PRP and PRF treatments begin with a simple blood draw. The process is comfortable and quick. After the blood is collected, it is placed in a centrifuge that separates the components needed for treatment. The final preparation is then applied or injected depending on your treatment plan.
Your appointment may include topical numbing for comfort. Many clients combine PRP or PRF with treatments like microneedling or other skin rejuvenation services. This creates layered benefits that improve overall results.
Most appointments last between 45 and 60 minutes. There is minimal downtime and most clients return to normal activities shortly after treatment.
How Soon You Will See Results
Regenerative treatments build results gradually. This is part of what makes them so natural looking.
PRP timeline
You may see a glow within days, with more noticeable improvements in two to six weeks.
PRF timeline
Because PRF releases growth factors slowly, results appear over several weeks and continue to build with each session.
PRF EZ Gel timeline
You may see subtle volume immediately, followed by deeper improvements in tone and elasticity as collagen rebuilds.
For best results, a series of treatments spaced several weeks apart is often recommended.
Why Regenerative Treatments Are Growing in Popularity
Clients love regenerative treatments because they look natural, feel authentic, and support long term skin health. PRP and PRF do not change your features. They enhance your natural beauty and help the skin repair itself. This aligns with the growing desire for subtle, balanced results.
These treatments also support whole skin health. They help improve hydration, circulation, collagen production, and cell turnover. Over time, your skin becomes stronger, brighter, and more resilient.
For clients who value natural beauty, regenerative aesthetics are an ideal choice.
Choosing Your Treatment at The Lounge at Healdsburg
Your skin is unique, and your treatment plan should be too. At The Lounge at Healdsburg, all regenerative treatments are performed by licensed medical professionals who understand both facial anatomy and the science behind PRP and PRF. During your consultation, we will evaluate your skin, listen to your goals, and recommend the option that fits you best.
Whether you choose PRP, PRF, or PRF EZ Gel, you will receive treatment that is safe, precise, and deeply personalized.
Begin Your Journey to Natural Rejuvenation
PRP and PRF are powerful ways to improve your skin using your own natural healing abilities. They offer subtle, long lasting results that help you look refreshed, balanced, and confident at every age.
If you are curious about which regenerative treatment is right for your skin, The Lounge at Healdsburg is here to guide you.
Glow naturally. Feel beautiful. Live balanced.
